Health Studies
Efficacy of Tai Chi on Pain, Stiffness and Function in Patients with Osteoarthritis

Osteoarthritis (OA) is one of the most frequent causes of pain, loss of function, and disability in adults in Western countries, occurring in the majority of people over 65 years of age and in roughly 80% of those over 75 years of age. No cure is currently available for OA and treatment options include primarily pharmacological or surgical treatment.

Taking into account the increasing prevalence of OA and associated disability, social, and economic costs, the American College of Rheumatology has developed guidelines for non-pharmacological therapy including exercise, education, physical therapy, at relatively low costs for OA sufferers. However, despite the potential benefits of exercise, very few OA patients participate in regular physical activity. The primary goals in the management of OA are currently to alleviate arthritic symptoms, including pain and stiffness, maintain or improve joint mobility and quality of life, increase muscle strength, and minimize the disabling effects of OA. 

 Rehabilitation is regarded as an effective non-pharmaceutical therapy in the management of OA. However, very few OA patients participate in any type of rehabilitation for fear of falling and exacerbating arthritic symptoms, which results in deconditioning and loss of physical function. Even those who participate in a rehabilitation program show poor adherence.

Recent studies have evaluated the role of TC, which enhances balance, strength, flexibility, and self-efficacy, and decreases pain and stiffness in various patients with chronic conditions. TC is a potential option for the management of OA and is superior to other forms of rehabilitation for elders because it involves a series of gentle fluid movements reputedly good for maintaining mobility and gradually improves muscle strength and range of motion without exacerbating arthritic symptoms. Growing evidence suggests that TC may reduce arthritic symptoms and/or improve physical function in patients with OA. 
Abstract:
Design:
A computerized search of PubMed and Embase (up to Sept 2012) was performed to identify relevant studies. The outcome measures were pain, stiffness, and physical function. Two investigators identified eligible studies and extracted data independently. The quality of the included studies was assessed by the Jadad score. Standard mean differences (SMDs) and 95% confidence intervals (CIs) were calculated and pooled using a random effects model. The change in outcomes from baseline was compared to the minimum clinically important difference. 
Participants:
A total of seven randomized controlled trials involving 348 patients with osteoarthritis met the inclusion criteria.
Results:
A total of seven randomized controlled trials involving 348 patients with osteoarthritis met the inclusion criteria. The mean Jadad score was 3.6. The pooled SMD was -0.45 (95% CI -0.70--0.20, P = 0.0005) for pain, -0.31 (95% CI -0.60--0.02, P = 0.04) for stiffness, and -0.61 (95% CI -0.85--0.37, P<0.00001) for physical function. A change of 32.2-36.4% in the outcomes was greater than the minimum clinically important difference. 

Conclusion:
Twelve-week Tai Chi is beneficial for improving arthritic symptoms and physical function in patients with osteoarthritis and should be included in rehabilitation programs. However, the evidence may be limited by potential biases; thus, larger scale randomized controlled trials are needed to confirm the current findings and investigate the long-term effects of Tai Chi. 
Link:
Yan, Jun-Hong et al. “Efficacy of Tai Chi on pain, stiffness and function in patients with osteoarthritis: a meta-analysis.” PloS one vol. 8,4 e61672. 19 Apr. 2013, doi:10.1371/journal.pone.0061672
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